Roberto Spreafico
Brussels Metropolitan Area Belgium
Summary
🤩
Rockstar🎓
Top SchoolRoberto Spreafico is a data science leader in discovery-stage biopharma, currently Vice President and Head of Discovery Data Science at Genmab, with 15+ years translating genomics and single-cell data into actionable drug-discovery insights. He has driven AI-assisted antibody discovery—developing deep learning generative models for antibody naturalness and binding affinity—and contributed computationally to programs that supported Sotrovimab’s preclinical development and IND. Roberto blends hands-on bioinformatics engineering (Nextflow pipelines, R/Shiny apps, AWS infra) with close experimental collaboration, notably rescuing lost antibody clones via sequencing innovations and optimizing high-throughput assays to produce higher-quality training data. He has led cross-functional teams, presented at leading antibody engineering conferences, and published work in preprint and peer contexts. Based in Brussels, he holds a PhD in Translational and Molecular Medicine and brings rare depth across wet-lab, computational, and regulatory domains.
10 years of coding experience
13 years of employment as a software developer
Doctor of Philosophy - PhD Translational and Molecular Medicine (Dissertation in Immunology), Doctor of Philosophy - PhD Translational and Molecular Medicine (Dissertation in Immunology) at Università degli Studi di Milano-Bicocca
English, Italian
Github Skills (144)
slurm10
dataflow10
package-management10
reproducible-science10
singularity10
nextflow10
bioconda10
conda10
reproducible-research10
recipes10
bioinformatics10
pipeline9
cli9
pipeline-framework9
genomics9
Programming languages (14)
Github contributions (5)
rspreafico/docker-busybox-bash
Jan 2018 - Feb 2018
Minimal Docker Container with bash
Contributions:6 pushes in 1 month
shelldockerdocker-containerbash
rspreafico/rspreafico.github.io
Mar 2019 - Mar 2019
Contributions:3 pushes, 1 branch in 1 day
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