Ales Varabyou

Senior Scientist at Johns Hopkins Whiting School of Engineering

Baltimore, Maryland, United States
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Summary

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Senior
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Top School
Ales Varabyou is a Senior Scientist and computational biologist with 11 years of experience building open-source software and scalable pipelines for large-scale genomic and transcriptomic analysis. He designs high-performance tools in Rust, C++, Python and SQL to scale RNA-seq and comparative genomics from single samples to hundreds of thousands, and has led projects such as TieBrush, ORFanage, and CHESS 3 that improved gene catalogues and isoform resolution. His work spans human and viral genomics, including pangenomic HIV-1 analyses and BoloTie, the first method to detect recombinant SARS-CoV-2 lineages from mass sequencing data. Based in Baltimore, he combines rigorous academic training (PhD in Computational Biology, MS in Computer Science) with production-oriented engineering at institutions like Johns Hopkins and PacBio. Notably, he focuses on practical open-source methods that make large-scale, reproducible comparative genomics accessible to the community.
code11 years of coding experience
job5 years of employment as a software developer
bookJohns Hopkins University
bookDoctor of Philosophy - PhD Computational Biology, Doctor of Philosophy - PhD Computational Biology at Johns Hopkins Whiting School of Engineering
bookBachelor's Degree Human Biology Computer Science, Bachelor's Degree Human Biology Computer Science at Luther College
bookhigh school Humanities/Humanistic Studies, high school Humanities/Humanistic Studies at Belarusian School of Humanities
bookHigh School Chemistry, High School Chemistry at UWC Maastricht
languagesEnglish, Russian, Russian, Polish, German, Spanish
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Github Skills (54)

summarize10
package-management10
conda10
bioinformatics10
bioconda10
bam9
sequencing9
genomics8
filter8
foreign7
gff6
c-library6
raspberry6
merge6
classify6

Programming languages (7)

TypeScriptC++ShellRCJupyter NotebookPython

Github contributions (5)

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LCRRS/Palmer

Dec 2014 - Oct 2015

Contributions:103 commits, 63 pushes, 7 branches in 10 months
flightraspberry-piautonomousroboticsled
alevar/chimFinder

Jun 2017 - Feb 2024

Foreign DNA/RNA integration site detection
Contributions:5 releases, 2 PRs, 79 pushes in 6 years 8 months
dnabioinformaticsforeignperlsite-integration
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Ales Varabyou - Senior Scientist at Johns Hopkins Whiting School of Engineering