Alexander Dilthey

Professor (W3-Universitätsprofessur) at Peptide Groove LLP

Dusseldorf, North Rhine-Westphalia, Germany
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Summary

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Senior
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Top School
Alexander Dilthey is a computational genomics professor and serial founder with 12+ years of experience developing algorithms and diagnostics for population-level sequencing, immunogenetics, long-read sequencing, microbiome analysis, and cell-free DNA. He leads a W3 professorship in Düsseldorf and co-founded two startups—one commercializing large-scale statistical HLA typing (licensed to ThermoFisher) and another building ctDNA-based cancer screening—bringing an unusual blend of deep statistical genetics (DPhil, Oxford) and product-focused commercialization. His work spans academic method development, real-time sequencing diagnostics (including SARS-CoV-2 genomic epidemiology), and scalable tooling for millions of samples. Equally comfortable in the lab and the boardroom, he has a track record of translating noisy long-read data into robust clinical and population-level insights. An early internet entrepreneur and consultant, he pairs technical entrepreneurship with a strong grounding in computer science and innovation practice.
code12 years of coding experience
job5 years of employment as a software developer
bookDPhil, Statistical Genetics, DPhil, Statistical Genetics at University of Oxford
bookScience Innovation Plus, Science Innovation Plus at University of Oxford - Said Business School
bookBachelor of Science (B.Sc.), Computer Science, 1.1, with distinction, Bachelor of Science (B.Sc.), Computer Science, 1.1, with distinction at Heinrich-Heine-Universität Düsseldorf
bookInternational relations & international law, International relations & international law at Université de Genève
languagesEnglish, German, French
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Github Skills (41)

genome10
taxonomy10
package-management10
conda10
ncbi10
hla10
rna-seq10
bioinformatics10
genomics10
bacteria10
metagenomics10
inference9
type-inference9
sequencing9
bioconda9

Programming languages (8)

JavaC++ShellCSCSSPerlHTMLPython

Github contributions (5)

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DiltheyLab/HLA-LA

Mar 2017 - Sep 2022

Fast HLA type inference from whole-genome data
Contributions:19 releases, 242 commits, 5 PRs in 5 years 6 months
hlagenomeinferencegenomicsbioinformatics
DiltheyLab/MetaMaps

Jul 2017 - Dec 2020

Long-read metagenomic analysis
Contributions:200 commits, 3 PRs, 64 pushes in 3 years 5 months
bacteriametagenomicsncbimetagenomic-analysisgenomics
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Alexander Dilthey - Professor (W3-Universitätsprofessur) at Peptide Groove LLP