Alexander Seeholzer
Principal Software Engineer at Isomorphic Labs
Lausanne Metropolitan Area Switzerland
Summary
🤩
Rockstar🎓
Top SchoolAlexander Seeholzer is a Principal Software Engineer and data technologist with over 12 years of experience applying mathematical modeling and data science to genomics and precision medicine. He combines rigorous academic training—a PhD from EPFL and a mathematics degree—with hands-on leadership roles building data platforms and engineering teams across industry and research. Alex excels at turning large, complex datasets into actionable products, having led data engineering at SOPHiA GENETICS and biotech firms before joining Isomorphic Labs. He contributes to open-source scientific tooling as a backend developer (notably extending neuron models in the widely used NEST simulator) and maintains a practical focus on maintainability and cross-version compatibility in production systems. Comfortable bridging disciplines, he also fosters creative, communicative teams and has run science-entertainment projects, reflecting an uncommon blend of technical depth and public-facing leadership.
12 years of coding experience
17 years of employment as a software developer
Diplom Mathematiker Mathematics, Diplom Mathematiker Mathematics at Ludwig-Maximilians-Universität MünchenDoctor of Philosophy - PhD Life Sciences, Doctor of Philosophy - PhD Life Sciences at EPFLHigh School Business/Commerce General, High School Business/Commerce General at Gynasium Erding
English, French, Spanish, Japanese, German
Github Skills (16)
database-migrations10
nest-simulator10
debug10
database-migration10
c-language10
cpp10
backend10
neurons10
cprogramming-language10
back-end-development10
nest10
python10
simulator10
django10
sa9
Programming languages (13)
Github contributions (5)
django-helpdesk/django-helpdesk
Feb 2015 - Jan 2017
A Django application to manage tickets for an internal helpdesk. Formerly known as Jutda Helpdesk.
Role in this project:
Back-end Developer
Back-end DeveloperContributions:53 commits, 29 PRs, 2 pushes in 1 year 11 months
Contributions summary:Alexander primarily contributed to the Django-based helpdesk application by implementing bug fixes and adding new features. Their work involved creating database migrations to add new fields to the queue model and adapting the codebase for compatibility with different Django versions. The user also addressed issues related to user settings and template rendering, ensuring the application's stability and functionality. These contributions demonstrate a focus on the core functionality and maintainability of the Django helpdesk system.
casespythonservicedesktrackerinternal
nest/nest-simulator
Oct 2015 - Mar 2016
The NEST simulator
Role in this project:Back-end Developer
Back-end DeveloperContributions:32 commits, 9 PRs, 64 comments in 5 months
Contributions summary:Alexander primarily contributed to extending the functionality of the `parrot_neuron` model within the NEST simulator. They added features to allow connections on ports 0 and 1, enabling the implementation of STDP protocols by allowing the setting of pre- and post-synaptic spike times. Furthermore, the user addressed formatting issues and added Python tests to verify the correct functionality of the extended features, including testing spike repetition and ignoring spikes on specific ports. These changes enhanced the simulator's capabilities for STDP protocol analysis.
cppnest-simulatorpythonsimulationneurons
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