Alexander Stram

Director, Bioinformatics Engineering

Del Mar, California, United States
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Summary

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Senior
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Top School
Alexander Stram is a bioinformatics engineering leader with 11 years of experience designing and optimizing high-throughput genomic pipelines, currently driving work at Personalis in Del Mar, CA. He has repeatedly scaled sequencing workflows—cutting compute costs by nearly half on a 90,000-sample contract, increasing pipeline parallelism 10x, and doubling read compression through novel preprocessing—while exploring FPGA/GPU acceleration for primary and secondary analysis. His background spans translational and commercial product launches (including liquid biopsy/Oncotype SEQ) and large cohort GWAS work at USC, blending deep algorithmic skill with practical HPC and cloud deployments. Alex pairs advanced mathematical training (MA in Mathematics) with hands-on systems engineering, and is known for reliably delivering high-quality, operationalized solutions that bridge R&D and production.
code11 years of coding experience
job15 years of employment as a software developer
bookM.A Mathematics, M.A Mathematics at University of Southern California
bookSt. Francis High School, La Canada, CA
bookLondon School of Economics and Political Science
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Github Skills (103)

slurm10
dataflow10
reproducible-science10
singularity10
nextflow10
pipeline10
bcftools10
tabix10
groovy10
dsl10
reproducible-research10
phasing10
samtools10
aws10
bioinformatics10

Programming languages (11)

TypeScriptC#C++RCScalaJavaScriptVim script

Github contributions (5)

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ahstram/al3c

Apr 2015 - Apr 2018

Contributions:18 commits, 14 PRs, 250 pushes in 3 years
golang
ahstram/transpos

Apr 2018 - Jul 2020

Contributions:2 pushes, 1 branch in 2 years 3 months
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Alexander Stram - Director, Bioinformatics Engineering