Andreas Prlić

Principal Software Engineer at Natera

San Diego, California, United States
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Summary

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Andreas Prlić is a Principal Software Engineer with 21 years of experience building scalable bioinformatics and clinical genomics platforms, now driving software at Natera from San Diego. He led development of Invitae’s interpretation platform that processes over a million clinical-grade NGS samples per year, scaled capacity by an order of magnitude, and contributed substantially to ClinVar submissions. Andreas combines hands-on full‑stack engineering, distributed computation and cloud migrations with technical leadership—authoring designs, reviewing architecture, and representing platforms in clinical and regulatory audits. His background includes leading the RCSB Protein Data Bank engineering efforts, massive parallelization of CPU-bound algorithms, and long-running stewardship of the BioJava open-source project. He mentors and hires engineering teams, bridges bioinformatics, clinical, and regulatory stakeholders, and has experience productionizing AI tools for genome interpretation. He holds a PhD in bioinformatics and is known for turning complex genomic analyses into auditable, scalable services.
code21 years of coding experience
job18 years of employment as a software developer
bookPhD, Bioinformatics, PhD, Bioinformatics at Universität Salzburg
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Github Skills (86)

blast10
symmetry10
3d-structure10
pdb10
transcript10
pip10
genomics10
computational-biology10
protein-sequences10
bam10
structural-biology10
ncbi10
pdb-files10
amino10
sequence-analysis10

Programming languages (8)

JavaShellMakefileSCSSJavaScriptJupyter NotebookCythonPython

Github contributions (5)

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rcsb/colorbrewer

Nov 2011 - Apr 2017

Contributions:52 commits, 15 pushes in 5 years 5 months
color-blindblindjavacolor-palettespalettes
biojava/rcsb-sequenceviewer

Jun 2010 - Oct 2016

PDB Amino Acid Sequence Viewer
Contributions:159 commits, 7 pushes, 4 comments in 6 years 5 months
sequencencbipdbsequence-viewerpdb-files
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Andreas Prlić - Principal Software Engineer at Natera