Ashis Saha
Computational Scientist 3
South San Francisco, California, United States
Summary
👤
Senior🎓
Top SchoolAshis Saha is a Computational Scientist with 12 years of experience who transforms large-scale genomics and clinical datasets into actionable insights to accelerate drug discovery and safety assessment. At Genentech he builds integrative multi-omics pipelines for therapeutic target prioritization and analyzes clinical trial genomics—including HLA, PRS, and variant associations—to understand immunotherapy response and adverse events. His PhD work at Johns Hopkins produced robust methods for eQTL, co-expression, and trans-eQTL analysis used in consortia like GTEx and eQTLGen, reflecting a strong foundation in reproducible, large-scale regulatory genomics. Comfortable bridging academic rigor and product-focused engineering, he pairs bioinformatics and AI/ML expertise with production-grade pipeline development. Based in South San Francisco, he brings both biological insight and software engineering discipline to biomarker discovery in oncology and autoimmune diseases. An often-overlooked strength is his track record of establishing best-practice workflows that reduce false positives in complex genetic analyses.
12 years of coding experience
7 years of employment as a software developer
Johns Hopkins UniversityMaster of Science (M.S.), Computer Engineering, Master of Science (M.S.), Computer Engineering at Korea UniversityB.Sc., Computer Science & Engineering, B.Sc., Computer Science & Engineering at Bangladesh University of Engineering and Technology
Github Skills (23)
seq10
gene-expression10
dimensionality-reduction9
single-cell-analysis9
bioinformatics9
transcriptomics9
tsne9
clustering9
rna-seq9
genomics8
sketch7
python7
data-visualization6
count-min-sketch5
data-integration4
Programming languages (3)
Github contributions (5)
battle-lab/twn_tsn
Dec 2016 - Mar 2018
Contributions:48 commits, 2 pushes, 1 branch in 1 year 2 months
alorchhota/ocm
Mar 2021 - Mar 2024
Offline (conservative) count-min sketch.
Contributions:2 PRs, 6 pushes, 1 branch in 3 years
offlinecount-min-sketchsketch
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