Azhar Khandekar
Postdoctoral Fellow at Fred Hutch
Seattle, Washington, United States
Summary
👤
Senior🎓
Top SchoolAzhar Khandekar is a postdoctoral fellow and computational biologist with nine years of research experience bridging wet-lab and computational approaches to genomics and cancer mutagenesis. Trained in biochemistry at the University of Washington and completing a PhD in Bioinformatics and Systems Biology at UC San Diego, he has investigated how methylation influences mutational processes and developed pipelines for sequencing and data analysis. His background spans hands-on molecular work (mouse models, DNA library prep) to algorithmic analysis at NIH and NCBI, enabling him to translate experimental questions into reproducible computational workflows. Currently at Fred Hutch, he aims to apply this dual expertise to biotech problems where integrative genomics drives therapeutic discovery. A detail many miss: he’s equally comfortable presenting at symposia and optimizing lab protocols, reflecting a rare blend of wet-lab pragmatism and dry-lab rigor.
9 years of coding experience
2 years of employment as a software developer
Bachelor of Science (BS), Biochemistry, Bachelor of Science (BS), Biochemistry at University of WashingtonCourseraHigh School Diploma, GPA 3.97, High School Diploma, GPA 3.97 at Mount Si High SchoolUniversity of California, San Diego
Hindi, English
Github Skills (22)
genome10
cancer-genomics10
bioinformatics10
bed10
genomes9
extraction8
signature8
probability8
mutation6
matrix6
python5
visualization5
nlp3
latent-dirichlet-allocation3
topic-modeling3
Programming languages (3)
Github contributions (5)
azhark2/SigProfilerMatrixGenerator
Jul 2020 - Jul 2024
SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations. It allows downsizing the generated mutations only to parts for the genome (e.g., exome or a custom BED file). The tool seamlessly integrates with other SigProfiler tools.
Contributions:22 pushes, 7 branches in 4 years 1 month
bedgenomematricesexomeparts
AlexandrovLab/SigProfilerMatrixGenerator
Jul 2020 - Nov 2022
SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations. It allows downsizing the generated mutations only to parts for the genome (e.g., exome or a custom BED file). The tool seamlessly integrates with other SigProfiler tools.
Contributions:23 commits, 26 PRs, 19 pushes in 2 years 4 months
bedgenomematricesmutation-analysisexome
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