Benedetto Polimeni

Research Scientist Bioinformatics

Milan, Lombardy, Italy
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Summary

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Benedetto Polimeni is a research scientist in bioinformatics with 8 years of experience studying the non-coding genome in immune systems and cancer, now based in Milan. He combines deep expertise in bulk and single-cell transcriptomics and epigenomics with hands-on experience in both short- and long-read sequencing, developing novel computational methods for emerging technologies. His PhD work produced the IRescue Python package to quantify transposable element expression in single-cell RNA-seq, and his research has helped define a new class of RNAs that regulate T cell quiescence and exhaustion. At the National Institute of Molecular Genetics he led integrative multi-omics studies and supervised junior bioinformaticians; he now advances bioinformatics at Istituto Italiano di Tecnologia. Known for translating complex datasets into biological insight, he is currently investigating how transposable elements shape human cell differentiation and identity.
code8 years of coding experience
bookUniversity of Milan
bookDoctor of Philosophy - PhD Translational and Molecular Medicine, Doctor of Philosophy - PhD Translational and Molecular Medicine at Università degli Studi di Milano-Bicocca
bookMaster's degree Cell/Cellular and Molecular Biology, Master's degree Cell/Cellular and Molecular Biology at Università degli Studi di Torino
bookBachelor's degree Biology/Biological Sciences General, Bachelor's degree Biology/Biological Sciences General at Università di Catania
languagesItalian, English
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Stackoverflow

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41reputation
3kreached
1answer
3questions
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Github Skills (92)

package-management10
windows10
seq10
tray10
structural-variation10
genomics10
nextflow10
rna-seq10
powershell10
bioconda10
cli10
conda10
pairwise10
installer10
filesystem10

Programming languages (12)

PowerShellC#TypeScriptRShellC++CTeX

Github contributions (5)

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bepoli/modules

Sep 2022 - Jan 2025

Repository to host tool-specific module files for the Nextflow DSL2 community!
Contributions:23 pushes, 10 branches in 2 years 4 months
hostnextflow-dsl2nextflowdsl2workflow
bodegalab/irescue

Sep 2022 - Jan 2023

Uncertainty-aware quantification of Transposable Elements expression in scRNA-seq
Contributions:9 releases, 2 reviews, 33 commits in 4 months
elementsscrnaseqscrna-seqbioinformaticstransposable-elements
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Benedetto Polimeni - Research Scientist Bioinformatics