Brandonย Malone
Principal Consultant Generative AI & De Novo Drug Discovery
Madison, Wisconsin, United States
Summary
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Top SchoolBrandon Malone is a Principal Consultant specializing in generative AI-driven de novo drug discovery, with over a decade of machine learning and bioinformatics experience focused on immuno-oncology and precision medicine. He has translated probabilistic and graph-based ML methods into clinical impactโleading a personalized cancer vaccine platform with sustained recurrence-free outcomes in a Phase I/II cohort and validating a Bayesian "digital twin" that produced a 70% immune response in donor samples. Brandon combines a PhD in machine learning with industry leadership at NEC OncoImmunity and NEC Labs, building regulatory-ready GenAI architectures that embed automated fact verification and citation traceability. He routinely bridges research and product, authoring 40+ papers in top AI and life-science venues while turning complex RNA and T-cell biology into deployable drug-discovery systems. Based in Madison, WI, he now consults on novel GenAI architectures and de novo small-molecule and mini-protein design, often favoring probabilistic approaches that make models interpretable and auditable for clinical translation.
10 years of coding experience
11 years of employment as a software developer
Ph.D., Machine Learning, Ph.D., Machine Learning at Mississippi State University
Github Skills (24)
predict10
bayesian10
occupancy10
feature-selection9
feature-extraction9
translation9
meta-learning9
automated-machine-learning9
hyperparameter-tuning9
python8
extraction8
dtw8
feature-engineering8
automl7
machine-learning7
Programming languages (2)
Github contributions (5)
bmmalone/pylifesci
May 2017 - Apr 2023
This repo contains bioinformatics-related scripts and helpers.
Contributions:4 PRs, 46 pushes, 2 branches in 5 years 11 months
dieterich-lab/rp-bp
Apr 2016 - Mar 2018
Rp-Bp is a Bayesian approach to predict, at base-pair resolution, ribosome occupancy and translation.
Contributions:407 commits, 293 pushes, 18 branches in 1 year 11 months
approachtranslationoccupancyresolutionmachine-learning
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