Brendan Miller

Senior Scientist, Computational Biology And Spatial Transcriptomics

Baltimore, Maryland, United States
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Summary

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Senior
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Top School
Brendan Miller is a computational biologist with 11 years of experience who translates complex spatial transcriptomics and cancer epigenetics datasets into robust, reproducible analysis pipelines. Currently a Senior Scientist at Merck after postdoctoral work at Johns Hopkins, he bridges wet-lab molecular expertise and advanced computational methods to accelerate biomarker discovery and spatially resolved biology. His PhD and NIH training focused on DNA methylation in cell-free DNA and CIMP tumor epigenetics, giving him deep experience with both experimental design and in silico integrative analyses. Brendan is notable for moving seamlessly between hands-on lab techniques (ddPCR, bisulfite sequencing) and scalable bioinformatics, enabling insights that span molecules to tissues. Based in Baltimore, he brings a pragmatic combination of academic rigor and industry-focused delivery to translational genomics projects.
code11 years of coding experience
job7 years of employment as a software developer
bookBachelor of Science (BS), Biochemistry, Bachelor of Science (BS), Biochemistry at University of Vermont
bookJohns Hopkins University
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Github Skills (33)

deconvolution10
spatial-transcriptomics10
spatially-resolved-transcriptomics10
gene-expression10
spatial-analysis9
transcriptomics9
sequence9
genomics8
bioconductor8
r-package8
bioinformatics7
spatial7
differential-expression6
r6
toolbox4

Programming languages (6)

RSCSSJavaScriptHTMLJupyter NotebookPython

Github contributions (5)

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JEFworks-Lab/STdeconvolve

Feb 2021 - Dec 2022

Reference-free cell-type deconvolution of multi-cellular spatially resolved transcriptomics data
Contributions:188 commits, 11 PRs, 136 pushes in 1 year 10 months
deconvolutionspatially-resolved-transcriptomics
bmill3r/data_cv

Sep 2021 - Jul 2025

Generate custom CV using R and CSS based on `datadrivencv`
Contributions:3 PRs, 21 pushes, 2 branches in 3 years 10 months
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