Brendan O'fallon

Bioinformatics Director

Salt Lake City, Utah, United States
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Summary

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Senior
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Top School
Brendan O'fallon is a seasoned clinical bioinformatics director with 15 years of experience applying human genetics, next-generation sequencing, and quantitative analysis to clinical and population-scale problems. He leads bioinformatics teams at ARUP Laboratories while maintaining senior bioinformatics responsibilities at 23andMe, bridging clinical diagnostics and consumer genomics. Brendan has a track record of building and supervising NGS informatics pipelines and software to support medical testing, and earlier research at University of Washington produced algorithms for inferring population history from sequence data. He holds a PhD in Biology from the University of Utah and a BA from Grinnell College, combining rigorous academic training with practical, production-focused delivery. Known for developing innovative and disruptive analytical methods, he brings both hands-on computational expertise and operational leadership to complex genomic projects. An often-underappreciated strength is his ability to translate research-grade algorithms into auditable clinical workflows that scale in regulated laboratory environments.
code15 years of coding experience
job2 years of employment as a software developer
bookBA, Biology, General, BA, Biology, General at Grinnell College
bookThe University of Utah
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Github Skills (73)

genomics10
bam10
fasta10
bcftools10
tabix10
sequencing10
phasing10
samtools10
java-api10
bedtools9
minhash9
genetic9
api9
htslib9
hts9

Programming languages (7)

JavaC++CHTMLJupyter NotebookCythonPython

Github contributions (5)

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ARUP-NGS/jenever

Feb 2024 - Feb 2025

Contributions:5 releases, 2 PRs, 106 pushes in 11 months
brendanofallon/SNPSVM

Sep 2012 - Dec 2013

Contributions:49 commits in 1 year 2 months
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Brendan O'fallon - Bioinformatics Director