Brett Smith
Software Engineer - Health Data Science
San Francisco, California, United States
Summary
👤
Senior🎓
Top SchoolBrett Smith is a software engineer specializing in health data science with a decade of experience translating multi-omic and clinical research needs into cloud-native, HIPAA-aware platforms and APIs. At the Institute for Systems Biology he builds OpenAPI services over Neo4j knowledge graphs and ranks results to support drug repurposing and clinical questions, while engineering AWS-based pipelines that power COVID-19, Alzheimer’s, and cancer studies. Previously at Arivale he optimized containerized genomics pipelines (cutting genetic processing times by 60%) and maintained research-ready snapshots and APIs to enable reproducible analysis. His background as a biologist and academic researcher gives him deep domain fluency in experimental design, sequencing analysis, and statistical methods—skills he pairs with production engineering to keep complex data flowing across multi-institution collaborations. Notably, he owns data-synchronization services that ensure rapid visibility of clinical data among distributed partners, reflecting a practical focus on operational reliability as well as analytical rigor.
10 years of coding experience
5 years of employment as a software developer
Bachelor's degree, Biology, Bachelor's degree, Biology at Pepperdine UniversityUniversity of California Santa Cruz
Github Skills (42)
biomedical10
translator9
nlp8
api8
karabiner8
keyboard8
macos-sierra8
relay7
macos6
owl6
agent6
json-api6
monarchinitiative5
testing4
translation4
Programming languages (4)
Github contributions (5)
suihuanglab/improving-agent
Feb 2020 - Feb 2025
An Autonomous Reasoning Agent in the NCATS Biomedical Translator Network that uses EHR and multi-omic cohorts to rank results from user queries
Contributions:1 release, 1 review, 136 PRs in 5 years
autonomousagentomicehrncats-translator
brettasmi/podrex
Jan 2018 - Jul 2018
Contributions:174 commits, 90 pushes, 1 branch in 5 months
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