Brian Capaldo
Bioinformatics Specialist
Washington DC-Baltimore Area United States
Summary
👤
Senior🎓
Top SchoolBrian Capaldo is a bioinformatics specialist with a Ph.D. in Biochemistry and Molecular Biology and over a decade of experience applying computational methods to single-cell and NGS datasets across cancer and immunology research. He builds and customizes R/Bioconductor pipelines for CyTOF, spectral cytometry, scRNA-seq, ChIP-seq and ATAC-seq and links functional genomics to clinical immunological endpoints using tools like Citrus and ggplot2. At the National Cancer Institute and prior roles at UVA he has driven integrative analyses—combining mass cytometry, proteomics, methylation and exome data—to generate biologically actionable hypotheses now underpinning manuscripts in preparation. Proficient in UNIX, Perl, bash and advanced visualization, he also brings hands-on mass spectrometry training from Northeastern’s computational proteomics program. Notably, he has a track record of translating complex, heterogeneous datasets into reproducible pipelines and clinically relevant insights that accelerate biomarker discovery.
10 years of coding experience
14 years of employment as a software developer
Johns Hopkins UniversityDoctor of Philosophy (Ph.D.) Biochemistry and Molecular Biology, Doctor of Philosophy (Ph.D.) Biochemistry and Molecular Biology at University of Virginia
English, Italian
Github Skills (39)
single-cell-genomics10
rna-seq10
bioinformatics10
genomics10
cran10
nextflow9
seq9
genome-assembly9
sequencing9
nf-core8
immunology8
pipeline8
chip-seq8
single-cell-analysis7
science6
Programming languages (7)
Github contributions (5)
CBIIT/lgcp
Feb 2019 - Jun 2021
Contributions:117 commits, 168 pushes, 2 branches in 2 years 4 months
bc2zb/scyttools
Oct 2019 - Apr 2024
Contributions:51 pushes, 1 branch in 4 years 5 months
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