Brian Cole
Senior Director Scientific Software at Treeline Biosciences
New York, New York, United States
Summary
👤
Senior🎓
Top SchoolBrian Cole is a Senior Director of Scientific Software based in New York with 11 years of experience building high-performance chemical informatics and drug-discovery tools. He combines deep systems and algorithmic skills in C++, C and Python with GPU/OpenCL expertise to accelerate cheminformatics workloads, and has led toolkit and GPU projects such as FastROCS. His tenure at OpenEye, D. E. Shaw Research, and Treeline reflects a track record of shipping production-grade scientific software and managing cross-functional engineering teams. An active contributor to the RDKit open-source project, he has improved core sanitization, exposed advanced stereochemistry APIs, and resolved tricky shared-library import issues, highlighting both low-level debugging chops and domain knowledge. Outside of engineering he has taught and run a martial arts school, a detail that underscores his leadership and discipline in unconventional settings.
11 years of coding experience
20 years of employment as a software developer
BS Computer Science, BS Computer Science at Temple University
Github Skills (7)
rdkit10
c-language10
cprogramming-language10
python10
cheminformatics10
cplus9
cpp9
Programming languages (4)
Github contributions (5)
rdkit/rdkit
Aug 2016 - Jan 2019
The official sources for the RDKit library
Role in this project:
Back-end Developer
Back-end DeveloperContributions:27 commits, 18 PRs, 106 comments in 2 years 5 months
Contributions summary:Brian contributed significantly to the RDKit library, focusing on improving its core functionality and API. Their work included addressing an `ImportError` related to shared libraries, improving the performance of the `Chem.SanitizeMol` function, and exposing new functionalities like `DetectBondStereoChemistry` and `ReplaceBond` to Python. Furthermore, the user added a feature for stereo enumeration and fixed string module conversion bugs.
cheminformaticsrdkitpythonc-plus-plussources
coleb/rdkit
Aug 2016 - Jan 2019
The official sources for the RDKit library
Contributions:24 pushes, 24 branches, 4 comments in 2 years 5 months
rdkitrdmasystems-programmingsources
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