Executive Director, Clinical Pharmacology at Madrigal Pharmaceuticals
Conshohocken, Pennsylvania, United States
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Summary
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Senior
🎓
Top School
Brian Schmidt is an executive clinical pharmacology leader with 12+ years translating mechanistic and systems-level models into actionable decisions across drug discovery and development. He has built and led ~30-person multidisciplinary teams at top pharma to apply QSP and PBPK frameworks from preclinical research through clinical trials, with a strong track record in oncology and immuno-oncology. A PhD-trained systems biologist and computational modeler, he couples deep academic experience in multi-omics and genome-scale modeling with pragmatic platform and tool development for industry use. Known for coaching PhD-level scientists into career-ready modelers, he blends technical mentorship with strategic portfolio impact. Based in Conshohocken, PA, he moves seamlessly between hands-on algorithm development and senior leadership roles that shape clinical pharmacology strategy.
12 years of coding experience
20 years of employment as a software developer
BS Chemical Engineering, BS Chemical Engineering at University of Pittsburgh
PhD Biomedical Engineering, PhD Biomedical Engineering at University of Virginia
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Brian Schmidt - Executive Director, Clinical Pharmacology at Madrigal Pharmaceuticals