Brian Tsui
Applied Scientist, HealthAI at Amazon
San Francisco Bay Area United States
Summary
👤
Senior🎓
Top SchoolBrian Tsui is an applied scientist with 11 years of experience applying machine learning, distributed computing, and complexity-theoretic ideas to translate high-dimensional biomedical and transactional data into production-ready systems. Currently at Amazon HealthAI, he leads GenAI-driven drug discovery efforts and previously pioneered Mixture-of-Experts research and fraud-evaluation pipelines for high-risk transactions. His background blends a PhD in bioinformatics and impactful industry work—optimizing DRAGEN methylation and HLA modules, helping enable the first sequencing-based FDA EUA COVID-19 test, and advancing liquid biopsy variant calling. He has a track record of squeezing performance from hardware and software (3x runtime improvements and 10x disk reductions) and adapting algorithms to run efficiently on compressed data. Based in Palo Alto, he brings both deep research pedigree (1,000+ citations from his PhD work) and hands-on production experience across AWS, Guardant Health, and Illumina. Colleagues rely on him to bridge rigorous algorithmic thinking with pragmatic engineering to move complex computational biology projects into scale.
11 years of coding experience
8 years of employment as a software developer
University of California, San Diego
English, Chinese
Stackoverflow
21reputation
1kreached
0answers
3questions
Github Skills (16)
aws7
gcp7
kubernetes6
assembly6
k8s6
linode6
x866
masm6
helm5
go5
kops5
bioinformatics3
depth3
coverage3
genomics2
Programming languages (4)
Github contributions (5)
brianyiktaktsui/DEEP_NLP
Jun 2018 - Aug 2020
Contributions:49 commits, 31 pushes, 1 branch in 2 years 1 month
brianyiktaktsui/Skymap
Nov 2017 - Mar 2018
Contributions:69 pushes, 1 branch in 3 months
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