Charles Plessy is a Staff Scientist based in Okinawa with 18 years of experience at the intersection of molecular biology and open-source software. He designs and applies DNA/RNA sequencing technologies to probe molecular mechanisms across marine biology and human health, translating complex lab methods into reproducible computational workflows. As a long-time Debian developer and active contributor to nf-core/modules, he has helped integrate LAST alignment tools into Nextflow DSL2 pipelines, improving reproducibility and scalability for sequence analysis. His career spans leadership and research roles at RIKEN and OIST, combining hands-on wet-lab expertise with pipeline engineering. Colleagues rely on him for pragmatic Free Software solutions that make advanced sequencing methods accessible beyond the lab. An uncommon but defining trait is his dual fluency in core computational infrastructure and field-focused biology, enabling cross-disciplinary projects from Antarctic research to Okinawan marine studies.
Repository to host tool-specific module files for the Nextflow DSL2 community!
Role in this project:
Backend Developer
Contributions:41 reviews, 9 commits, 32 PRs in 2 months
Contributions summary:Charles contributed significantly to the `nf-core/modules` repository, focusing on the development of modules for the Nextflow DSL2 framework. Their work involved creating new modules for the LAST suite of bioinformatics tools, including `lastdb`, `mafswap`, `lastal`, `dotplot`, and `postmask`. These modules streamline the integration of LAST tools within Nextflow pipelines, enhancing the capabilities for sequence alignment and analysis. They also fixed bugs and updated code to be compatible with the latest versions of LAST and Nextflow.
Draft workflow for pairwise genome comparison. We recommend you use the new nf-core version instead: https://nf-cor.e/pairgenomealign
Contributions:2 reviews, 76 commits, 19 PRs in 1 year 6 months
genomepipelinepairwisecomparisongenomics
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