Chris Hoefler
Principal Scientist, Bioinformatics, Precision Oncology
Cambridge, Massachusetts, United States
Summary
👤
Senior🎓
Top SchoolChris Hoefler is a Principal Scientist in Bioinformatics focused on precision oncology, with nine years of computational biology experience and a deep academic foundation in enzymology and chemical biology (PhD). He designs and implements multi-omic and single-cell analysis pipelines—spanning RNAseq, scRNAseq, metabolomics, SNV annotation, and multi-modal integration—to support discovery, translational cohorts, and biomarker-driven projects. Chris has led multidisciplinary teams across industry and academia, applying statistical learning, knowledge graphs, trajectory analysis, and machine learning to complex biological assays and biosensor/tissue-engineering platforms. His background in natural product metabolism and microbial competition gives him a unique mechanistic perspective when interpreting metabolic and pathway-level signals in human and preclinical data. Based in Cambridge, MA, he combines hands-on method development with project leadership at the interface of computational biology and experimental systems. Colleagues rely on him to bridge wet-lab nuance and scalable computational workflows for actionable insights in oncology and beyond.
9 years of coding experience
6 years of employment as a software developer
BA, Biochemistry and Molecular Biology, BA, Biochemistry and Molecular Biology at Reed CollegeDoctor of Philosophy (PhD), Biochemistry, Doctor of Philosophy (PhD), Biochemistry at Brandeis University
Github Skills (30)
web-application9
connectivity9
perl9
tiddlywiki9
foswiki9
database-connectivity9
mercurial8
version-control8
r-package7
java7
powerpoint7
cop7
database6
cran6
r6
Programming languages (4)
Github contributions (5)
hoeflerb/distro
Aug 2017 - Aug 2017
Contributions:3 pushes, 2 branches in 1 day
foswikiextensionsstart-heremonolithdistribution
foswiki/JsonSQLPlugin
Aug 2017 - Aug 2017
Contributions:1 push, 2 branches, 1 tag in 1 day
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