Collin Tokheim
Associate Director
Waltham, Massachusetts, United States
Summary
👤
Senior🎓
Top SchoolCollin Tokheim is an Associate Director in Oncology Data Science & AI at AstraZeneca with 13 years of experience applying machine learning and bioinformatics to cancer discovery and drug development. He has led small interdisciplinary teams to build computational frameworks for Targeted Protein Degradation, contributed to multiple lead optimization and investment decisions, and proactively discovered new therapeutic targets advanced into validation and a drug program. His postdoctoral and graduate work produced machine learning methods and high-impact publications (Cell, Molecular Cell, Nature Communications) that link somatic mutations and proteomic changes to cancer biology. Based in Waltham, MA, Collin blends deep methodological rigor with translational impact—often turning complex multi-omic datasets into actionable insights for oncology programs.
13 years of coding experience
10 years of employment as a software developer
Doctor of Philosophy - PhD Bioengineering and Biomedical Engineering, Doctor of Philosophy - PhD Bioengineering and Biomedical Engineering at The Johns Hopkins University School of MedicineBachelor of Science in Engineering (BSE) Biomedical Engineering, Bachelor of Science in Engineering (BSE) Biomedical Engineering at University of Iowa
English
Github Skills (22)
genes10
predict10
hotspot10
randomization10
bioinformatics10
random-forest10
python9
machine-learning9
protein-structure9
scientific-computing8
scipy8
algorithms8
chainer8
deep-learning6
pytorch6
Programming languages (4)
Github contributions (5)
KarchinLab/2020plus
Oct 2013 - Sep 2020
Classifies genes as an oncogene, tumor suppressor gene, or as a non-driver gene by using Random Forests
Contributions:10 releases, 704 commits, 140 pushes in 7 years
random-forestmachine-learningsomatic-variantscancerbioinformatics
KarchinLab/HotMAPS_2016
Nov 2015 - Aug 2018
Detects hotspot regions for somatic mutations in 3D protein structures
Contributions:7 releases, 80 commits, 4 PRs in 2 years 9 months
cancerexome-scalehotspothotspot-regionsmissense-mutations
Find and Hire Top DevelopersWe’ve analyzed the programming source code of over 60 million software developers on GitHub and scored them by 50,000 skills. Sign-up on Prog,AI to search for software developers.