Cyriac Kandoth
Senior Data Scientist
Pennsylvania, United States
Summary
👤
Senior🎓
Top SchoolCyriac Kandoth is a Senior Data Scientist and engineering leader with 12+ years building reproducible, repurposable bioinformatics tools for human genetics and clinical sequencing programs. He has led teams and operations at institutions including UCLA Health, MSKCC, and the University of Pennsylvania, delivering production pipelines, clinical validation for large cancer panels, and an Azure-based clinical whole genome stack. A hands-on developer and primary implementer of widely used tools like vcf2maf, he blends software engineering rigor with genomics domain expertise to make complex analyses auditable and portable. He co-founded a clinical decision-support service and has a PhD in computer science, bringing both product-minded coordination across multidisciplinary teams and deep technical authorship in NGS workflows. Now based in Pennsylvania, he is transitioning his impact-oriented tooling and reproducibility focus toward civic tech and data journalism.
12 years of coding experience
15 years of employment as a software developer
Doctor of Philosophy - PhD Computer Science, Doctor of Philosophy - PhD Computer Science at Missouri University of Science and TechnologyBachelor of Science - BS Computer Science and Engineering, Bachelor of Science - BS Computer Science and Engineering at Model Engineering College
Stackoverflow
1reputation
0reached
0answers
0questions
Github Skills (3)
bioinformatics10
perl10
vcf-files10
Programming languages (10)
Github contributions (5)
mskcc/vcf2maf
Nov 2013 - Apr 2021
Convert a VCF into a MAF, where each variant is annotated to only one of all possible gene isoforms
Role in this project:
Back-end Developer
Back-end DeveloperContributions:54 releases, 4 reviews, 310 commits in 7 years 6 months
Contributions summary:Cyriac appears to be the primary developer responsible for the initial implementation of the `vcf2maf.pl` script. Their contributions involved setting up the script, defining MAF header columns, integrating the use of `snpEff` for variant annotation and handling of different variant types (SNPs, insertions, and deletions). Further work included updating documentation and adding support for multi-nucleotide polymorphisms (MNPs). Additionally, the user refactored some minor elements of the code such as improving checks and error handling.
genomicsvepmafbioinformaticsgene
mskcc/vcf_accuracy
Nov 2015 - Dec 2019
Contributions:10 pushes, 5 comments, 6 issues in 4 years 1 month
Find and Hire Top DevelopersWe’ve analyzed the programming source code of over 60 million software developers on GitHub and scored them by 50,000 skills. Sign-up on Prog,AI to search for software developers.