David Humphreys

Manager Of Genomics Core at Victor Chang Cardiac Research Institute

Greater Sydney Area Australia
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Summary

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Senior
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Top School
David Humphreys is a genomics core leader and RNA biologist/bioinformatician with 13+ years’ experience bridging molecular biology and computational analysis at the Victor Chang Cardiac Research Institute. Trained in both Biology and Computer Science, he discovered seminal mechanisms of miRNA-mediated mRNA degradation during his PhD and postdoc work and has since pivoted to deep sequencing technologies and RNA-Seq analysis. As Manager of the Genomics Core he runs the Proton sequencer, advises on experimental design, writes grants, and delivers end-to-end bioinformatic pipelines for RNA-Seq and whole exome/genome projects. He is the author of RNA-Seq tools including miRspring and Ularcirc, and maintains active collaborations exploring miRNA processing variants and non-coding RNAs in cardiac development. Known for combining hands-on wet-lab expertise with software development, he brings both operational leadership and method development to translational genomics workflows.
code13 years of coding experience
job15 years of employment as a software developer
bookPhD, Cell & molecular biology, PhD, Cell & molecular biology at University of Wollongong
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Github Skills (19)

seq10
transcript10
rna-seq10
htmlwidgets9
sequencing9
bioinformatics9
transcriptomics9
genomics9
python-bindings9
shiny7
bioconductor7
kallisto7
pipeline5
nextflow5
nf-core3

Programming languages (5)

RCNextflowJupyter NotebookPython

Github contributions (5)

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VCCRI/Ularcirc

Mar 2018 - Apr 2022

Contributions:96 commits, 88 pushes, 1 branch in 4 years 1 month
VCCRI/ShinyCell

Mar 2023 - Feb 2025

Shiny Interactive Web Apps for Single-Cell Data
Contributions:2 PRs, 12 pushes, 1 branch in 2 years
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David Humphreys - Manager Of Genomics Core at Victor Chang Cardiac Research Institute