DKTK Junior Group Leader at DKFZ German Cancer Research Center
Dusseldorf, North Rhine-Westphalia, Germany
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Summary
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David Koppstein is a DKTK Junior Group Leader specializing in cancer bioinformatics and multiomics, leading work at DKFZ/Uniklinikum Düsseldorf that leverages third-generation sequencing to map transcriptomic and genomic alterations in blood and brain cancers. With 17 years of experience spanning academia and industry, he blends deep computational expertise from roles at Max Planck, Max Delbrück Center, and Juno Therapeutics with hands-on wet-lab collaboration on spatial and long-read RNA sequencing. His PhD from MIT and earlier training at Yale underpin a track record of method development for single-cell, immunosequencing, and spatial transcriptomics, and he has secured and administered grants from major funders including the Chan-Zuckerberg Initiative. He has led pipeline architecture and interim data science management in translational settings, mentoring students and guiding cross-disciplinary teams. Notably, his recent focus on Nanopore long reads and 10X Visium spatial data targets aberrant RNA isoforms in neurological and cancer models—an approach that bridges clinical samples and cutting-edge sequencing technologies.
17 years of coding experience
7 years of employment as a software developer
Doctor of Philosophy (Ph.D.), Biology, Doctor of Philosophy (Ph.D.), Biology at Massachusetts Institute of Technology
Bachelor’s Degree, Molecular Biophysics and Biochemistry, Bachelor’s Degree, Molecular Biophysics and Biochemistry at Yale University
Contributions:48 pushes, 2 branches in 7 years 6 months
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David Koppstein - DKTK Junior Group Leader at DKFZ German Cancer Research Center