David Seifert

Principal Software Engineer at PacBio

Birsfelden, Basel-Landschaft, Switzerland
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Summary

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David Seifert is a Principal Software Engineer with nine years of experience specializing in bioinformatics and life-sciences software, currently leading engineering efforts at PacBio. Trained at ETH Zürich with a doctorate in computational biology and earlier degrees in biotechnology, he blends deep domain expertise with hands-on systems engineering—from low-level automation to large-scale refactors. At PacBio he has advanced from senior software roles to principal engineer, driving production-grade tooling and infrastructure for genomics. An active open-source contributor, he automated Bioconda packaging and build pipelines for PacBio tools, improving reproducible distribution across the bioinformatics ecosystem. Known for bridging research and production, he brings interdisciplinary rigor and a pragmatic focus on shipping reliable, maintainable software.
code9 years of coding experience
job8 years of employment as a software developer
bookDoctor of Science Computational Biology, Doctor of Science Computational Biology at ETH Zürich
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Github Skills (12)

mesonbuild10
sh10
conda10
script10
mson10
shell10
package-management10
scripting10
bioinformatics9
python8
docker4
dockers4

Programming languages (8)

ShellC++CHTMLCythonRakuPythonCuda

Github contributions (5)

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bioconda/bioconda-recipes

May 2018 - Mar 2021

Conda recipes for the bioconda channel.
Role in this project:
userAutomation Engineer
Contributions:47 reviews, 65 commits, 121 PRs in 2 years 10 months
Contributions summary:David primarily contributed to the automation of the build and deployment process for PacBio tools within the Bioconda ecosystem. This involved writing shell scripts (build.sh, post-link.sh) to set up the build environment using tools like Meson and install the software, along with adding disclaimers. The user also bumped versions of PacBio-related tools like `pbcore`, `pbcommand`, and `genomicconsensus`. Their work significantly contributed to the packaging and distribution of PacBio's bioinformatics tools.
biocondacondabioinformaticspackage-management
PacificBiosciences/pbmm2

Aug 2018 - Sep 2022

A minimap2 frontend for PacBio native data formats
Contributions:82 commits, 3 comments, 1 issue in 4 years 2 months
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