Demetri Nicolaou is a software engineer with eight years of experience building high-performance bioinformatics and ML infrastructure, currently applying his expertise at Stripe. He led development of GRAIL’s clinical-grade bioinformatics pipelines in Go, invented contamination-detection algorithms that improved model sensitivity, and helped validate pipeline modules in a >20,000-sample clinical study. Comfortable across Golang, Python, TensorFlow, and workflow systems like Reflow, he has optimized large-scale workflows (including a 20% memory reduction) and crafted FDA-focused documentation and testing frameworks. Demetri blends hands-on algorithm design with production engineering and mentorship—he’s mentored teams on CI/CD and helped resolve sample swaps in cohorts of 10,000+ patients—bringing a rare mix of regulatory, clinical, and systems-level perspective to data-driven product delivery.
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