Denis Puthier is a Full Professor in Genomics and Bioinformatics at Aix-Marseille Université with over 11 years of experience leading research and training in transcriptomics, epigenomics, spatial transcriptomics and non-coding RNA biology. He co-heads the TGML sequencing platform and serves as Deputy Director for Education at the MarMaRa Institute, combining hands-on sequencing operations with academic leadership. Denis develops practical bioinformatics tools—most notably the Python GTF toolkit (pygtftk) and the Scigenex R package—for reproducible functional annotation and single-cell/spatial analyses, reflecting his emphasis on usable software for genomics. Trained from bench to computation (PhD and postdoc in molecular biology/immunology, HDR in transcriptome bioinformatics), he blends wet-lab insight with engineering of workflows (Snakemake, Nextflow, Galaxy) and teaches a broad range of programming and statistical methods. An underappreciated strength is his focus on quality management in core facilities (ISO-certified TGML), ensuring that large-scale sequencing projects meet rigorous standards.
Habilitation à diriger des recherches (HDR), Bioinformtics and genomics, Titre: Analyse moléculaire et bioinformatique du transcriptome, Habilitation à diriger des recherches (HDR), Bioinformtics and genomics, Titre: Analyse moléculaire et bioinformatique du transcriptome at Aix-Marseille Université
PhD, Expression and regulation of the Bcl-2 family proteins in human myeloma cells, PhD, Expression and regulation of the Bcl-2 family proteins in human myeloma cells at EPHE
A python package and a set of shell commands to handle GTF files
Contributions:33 releases, 999 commits, 7 PRs in 4 years 7 months
bedpythonbioinformaticsshelltts
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Denis Puthier - Professor In Genomics And Bioinformatics