Derrick Wood is a computational biologist and founder with 12 years of experience building high-performance bioinformatics software and leading R&D teams to translate sequencing data into diagnostics and products. He architected and optimized foundational tools—most notably upgrading the Kraken taxonomic classifier to Kraken 2, cutting memory use by ~85% and boosting speed—which underpins much of modern metagenomic analysis. Derrick has driven machine-learning approaches that materially improved clinical variant calling (halving false negatives and reducing false discoveries by over 90%) and engineered pipelines that made complex workflows 10–100x faster without sacrificing accuracy. As a principal scientist and recent founder in Baltimore, he combines hands-on backend development with strategic product work across startups and industry leaders like Exact Sciences and Personal Genome Diagnostics. He also brings academic rigor from a CS PhD and a track record of mentoring students and interns while shipping production-grade open-source and proprietary systems.
12 years of coding experience
15 years of employment as a software developer
University of Texas at San Antonio
Doctor of Philosophy (Ph.D.) Computer Science, Doctor of Philosophy (Ph.D.) Computer Science at University of Maryland
The second version of the Kraken taxonomic sequence classification system
Role in this project:
Back-end Developer
Contributions:7 releases, 101 commits, 17 PRs in 4 years 7 months
Contributions summary:Derrick primarily contributed to the Kraken 2 taxonomic sequence classification system by making enhancements and fixes to the codebase. Their work included refactoring code, updating documentation, and fixing various bugs within the project. The user also added new features such as the deterministic build option and k-mer data reporting, along with improvements to the build process.
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Derrick Wood - Founder at Blackjack Biotechnologies