Didac Santesmasses
Senior Scientist II at GC Therapeutics
Cambridge, Massachusetts, United States
Summary
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Senior🎓
Top SchoolDidac Santesmasses is a computational biologist with 11 years of experience building scalable NGS pipelines and analytical frameworks to advance genomic safety and therapeutic technologies. He combines deep expertise in genomics, transcriptomics, single-cell RNA-seq, WGS and integration site/CRISPR off-target discovery with hands-on engineering of reproducible pipelines (Nextflow/Snakemake, Docker, AWS). His trajectory spans academic discovery—PhD and postdoctoral work on translation, readthrough and protein-truncating variants at CRG and Harvard—to industry roles developing off-target detection and safety analytics for gene-editing therapeutics. Based in Cambridge, MA, he is equally comfortable interpreting complex cohort datasets (gnomAD, UK Biobank, GTEx) and producing production-ready, collaborative codebases. A not-so-obvious strength is his sustained focus on functional annotation across diverse resources (RefSeq, gencode, COSMIC) to bridge basic biology and regulatory-grade genomic safety assessments.
11 years of coding experience
9 years of employment as a software developer
Doctor of Philosophy - PhD, Bioinformatics, Doctor of Philosophy - PhD, Bioinformatics at Universitat Pompeu Fabra
Catalan, Spanish, English
Github Skills (3)
genes4
chain2
bioinformatics2
Programming languages (1)
Github contributions (5)
didacs/ggsunburst
Mar 2019 - Sep 2020
Contributions:14 commits, 12 pushes, 1 branch in 1 year 6 months
didacs/ggtex
Jun 2015 - Oct 2015
Contributions:54 pushes, 1 branch in 4 months
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