Douglas Hoffman

Software Engineer at National Institutes of Health

Bethesda, Maryland, United States
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Summary

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Senior
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Douglas Hoffman is a seasoned software engineer with over 12 years of experience building web, database, and application software across government, research, and private sectors. With an MS in Computer Science from Johns Hopkins and a long tenure at the National Institutes of Health, he has delivered bioinformatics and forensics services such as ClinVar, MedGen, OSIRIS, and PheGenI using a wide technology stack from Python/Django and JavaScript to C++ and MS SQL Server. He combines legacy systems expertise (Fortran, VAX/VMS, SunOS) with modern web and data-driven development, enabling robust, long-lived scientific infrastructure. Based in Bethesda, MD, Douglas is comfortable navigating cross-platform environments (Windows, Linux, macOS) and has a knack for integrating graphical UIs and image processing into data-centric applications—an uncommon blend that supports both researcher-facing tools and backend services.
code12 years of coding experience
job13 years of employment as a software developer
bookJohns Hopkins University
bookBachelor of Science (BS), Systems Analysis, Bachelor of Science (BS), Systems Analysis at Miami University
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Github Skills (15)

quality-assurance10
derived10
multiplex10
tandem10
hid10
protocols10
biomedical10
marker10
analytical10
abi8
toolchain8
modular8
clang7
llvm6
compiler5

Programming languages (3)

C++LLVMTSQL

Github contributions (4)

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ncbi/osirisexport

Jul 2017 - Apr 2019

Contributions:17 commits, 5 pushes, 1 branch in 1 year 8 months
ncbi/osiris

Jan 2014 - Nov 2021

OSIRIS is a public domain quality assurance software package that facilitates the assessment of multiplex short tandem repeat (STR) DNA profiles based on laboratory-specific protocols. OSIRIS evaluates the raw electrophoresis data contained in .fsa or .hid files using an independently derived mathematically-based sizing algorithm. OSIRIS currently supports ABI capillary analytical platforms and numerous commercially available marker kits including all CODIS-compliant kits as well as those favored by biomedical laboratories.
Contributions:1200 commits, 8 PRs, 91 pushes in 7 years 11 months
strtandemdnalaboratoryfacilitates
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