Eachan Johnson
Group Leader at The Francis Crick Institute
London, England, United Kingdom
Summary
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Senior🎓
Top SchoolEachan Johnson is a group leader at the Francis Crick Institute who combines genetics, chemical biology and machine learning to design innovative antimicrobial strategies. With 11 years of research experience spanning the Broad Institute, Harvard/Mass General and a DPhil from Oxford, he applies large-scale functional genomics and chemical screening to tackle drug-resistant infection. His work blends whole-cell and target-based screening paradigms with computational models to accelerate discovery against pathogens such as Mycobacterium tuberculosis. He has a track record of engineering biochemical systems—from improved CYP:ferredoxin constructs to novel ferredoxins—and translating mechanistic insight into screening-ready assays. Based in London, he leads a systems chemical biology lab that bridges deep molecular biophysics and scalable, data-driven drug discovery. Notably, he pairs hands-on chemistry and assay development with machine learning to extract actionable signals from complex genomics screens.
11 years of coding experience
7 years of employment as a software developer
Master of Chemistry (MChem), Chemistry, First Class Honours (~4.0 GPA), Master of Chemistry (MChem), Chemistry, First Class Honours (~4.0 GPA) at University of Oxford
Stackoverflow
1reputation
0reached
0answers
0questions
Github Skills (12)
bioinformatics9
fitness5
chemistry4
cheminformatics3
error-handling3
graceful3
data-files2
inference2
tidy2
csv1
python1
softmax1
Programming languages (4)
Github contributions (5)
scbirlab/schemist
Feb 2024 - Mar 2025
Contributions:8 releases, 14 PRs, 66 pushes in 1 year
scbirlab/nf-sbrnaseq
Jun 2023 - Feb 2025
Nextflow pipeline to process demultiplexed Illumina paired-end FASTQ files from multiple bacterial samples into a gene x cell count table.
Contributions:10 PRs, 32 pushes, 9 branches in 1 year 8 months
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