Francesco Iorio
Senior Research Group Leader at Human Technopole
Legnano, Lombardy, Italy
Summary
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Senior🎓
Top SchoolFrancesco Iorio is a computational biologist and senior research group leader with over a decade of experience developing algorithms and software for chemo-genomic and genome-editing screens, drug discovery and cancer dependency mapping. He has led teams at Human Technopole and the Wellcome Sanger Institute, producing statistical and network-based methods to infer gene regulatory programs, synthetic lethalities, and drug repurposing opportunities from large-scale functional genomics data. His work blends machine learning, statistics, combinatorics and complex network theory to translate high-dimensional assays into actionable therapeutic hypotheses. Notably, his academic collaborations yield an Erdős number of 3, reflecting strong ties to the theoretical community behind his quantitative approaches. Based in Legnano, Italy, he advises biotech ventures while continuing visiting scientist work at EMBL-EBI, bridging fundamental research and translational impact.
10 years of coding experience
6 years of employment as a software developer
Master's Degree (Laurea v.o.) Computer Science, Master's Degree (Laurea v.o.) Computer Science at Università degli Studi di Salerno / University of Salerno
Italian, English
Github Skills (11)
genes10
r-package9
fitness9
genome9
knock9
genomics8
bioinformatics8
six8
shiny7
benchmarking6
variance3
Programming languages (3)
Github contributions (5)
DepMap-Analytics/HT29benchmark
Dec 2019 - Sep 2022
R package for benchmarking genome-wide CRISPR-Cas9 knock-out viability screening pipelines making use of a reference dataset from six high-quality screens of the HT29 cell line
Contributions:5 reviews, 21 commits, 5 PRs in 2 years 9 months
crispr-cas9r-packagecrisprbenchmarkinggenome
francescojm/CRISPRcleanR
Aug 2018 - Nov 2022
Contributions:45 commits, 91 pushes, 1 branch in 4 years 3 months
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