Gabriel Rocklin
Assistant Professor at Northwestern University
Chicago, Illinois, United States
Summary
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Senior🎓
Top SchoolGabriel Rocklin is an Assistant Professor and protein design researcher based in Chicago with nine years of postdoctoral and faculty experience developing high-throughput methods for protein biophysics and therapeutics. He leads a lab that combines de novo computational protein design with display selections, mass spectrometry proteomics, and next-generation sequencing to test thousands of variants in parallel and accelerate design-test-analyze cycles. His work addresses fundamental questions about how sequence and structure dictate folding stability, dynamics, and resistance to aggregation or degradation, and aims to build quantitative models that predict these phenotypes from genotype. Trained as a biophysicist with a PhD from UCSF and experience in the Baker lab at UW, he bridges rigorous free-energy calculation approaches with large-scale experimental pipelines. Unusually, his group pairs classical computational modeling with very high-throughput experimental selection to directly iterate and validate predictive models for therapeutic protein optimization.
9 years of coding experience
Bachelor of Arts (B.A.), Biology-Chemistry, History, Bachelor of Arts (B.A.), Biology-Chemistry, History at Claremont McKenna CollegeDoctor of Philosophy (Ph.D.), Biophysics, Doctor of Philosophy (Ph.D.), Biophysics at University of California, San Francisco
Github Skills (8)
mass2
dia2
top-down2
dda1
mass-spectrometry1
bottom-up1
yang1
bottom1
Programming languages (1)
Github contributions (4)
asford/protease_experimental_analysis
Oct 2016 - May 2017
Contributions:27 commits in 6 months
grocklin/hxtools
Aug 2018 - Aug 2018
Contributions:1 push, 1 branch in 1 day
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