George Amanakis

Cardiology Fellow at Hannover MEd

Hanover, Lower Saxony, Germany
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Summary

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Rockstar
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George Amanakis is a cardiology fellow and physician-scientist with 11 years of clinical and research experience focused on myocardial ischemia/reperfusion injury and redox-sensitive regulation of cardiac cell death. He earned his MD from the University of Crete and completed doctoral research at the University of Duisburg-Essen before a research fellowship at the NIH’s Laboratory of Cardiac Physiology. George balances translational cardiac research with active clinical roles at Hannover Medical School, aiming to move molecular insights into patient therapies. Unusually for a clinician-scientist, he is also a seasoned open-source contributor to core infrastructure projects like OpenZFS and the Linux kernel, improving L2ARC persistence and zpool split behavior. This blend of deep bench-to-bedside expertise and low-level systems coding gives him a pragmatic, systems-oriented approach to problem solving. His long-term goal is to establish an independent research program that translates mechanisms of myocardial cell death into clinical interventions.
code10 years of coding experience
bookDoctor of Medicine (M.D.), Medicine, Doctor of Medicine (M.D.), Medicine at University of Crete
bookDr. med., Medicine, Dr. med., Medicine at University of Duisburg-Essen
languagesGerman, Greek, English, French
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Github Skills (10)

c1710
caching10
error-handling10
filesystem10
openzfs10
c1110
zfs10
data-structure9
data-structures9
code-optimization9

Programming languages (7)

JavaC++ShellCPHPPerlPython

Github contributions (5)

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openzfs/zfs

Jan 2018 - Jan 2023

OpenZFS on Linux and FreeBSD
Role in this project:
userBack-end Developer
Contributions:145 reviews, 56 commits, 93 PRs in 5 years
Contributions summary:George's contributions primarily revolve around the ZFS file system's L2ARC (Level 2 Adaptive Replacement Cache) functionality. They implemented fixes and optimizations related to persistent L2ARC metadata, ensuring data integrity and performance after reboots. The user also worked on enhancing the `zpool split` command to support indirect vdevs and addressed several bugs and potential issues in the codebase. Furthermore, the user contributed to refining error reporting and handling in the ZFS system.
openzfstarballlinuxfreebsdsystem-software
gamanakis/zfs

Nov 2019 - Apr 2025

ZFS on Linux - the official OpenZFS implementation for Linux.
Contributions:1384 pushes, 125 branches in 5 years 5 months
openzfslinux-distributionlinuxzfsinitramfs
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George Amanakis - Cardiology Fellow at Hannover MEd