George Spracklin

Senior Bioinformatics Engineer

Boston, Massachusetts, United States
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Summary

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Senior
🎓
Top School
George Spracklin is a Senior Bioinformatics Engineer with nine years of experience translating complex genomics and epigenetics research into scalable computational pipelines for both academia and industry. He has driven discovery from bench to cloud—developing novel sequencing methods like Protect-seq, applying machine learning and polymer simulations to chromatin architecture at MIT, and delivering precision genomics workflows at Moderna and now Roche for the SBX platform. His toolkit spans Python, NGS, Hi-C/HiChIP, nanopore base-modification analysis, and cloud-native pipeline deployment, enabling rapid, reproducible analysis for clinical and research genomics. Colleagues describe him as equally comfortable designing wet-lab experiments and automating their analysis, with a habit of turning methodological inventiveness into practical, cost- and time-saving tools. Based in Boston, he combines rigorous PhD training in genetics with a track record of cross-disciplinary collaboration that uncovers unexpected biology in nuclear organization.
code9 years of coding experience
job8 years of employment as a software developer
bookDoctor of Philosophy (PhD) Genetics, Doctor of Philosophy (PhD) Genetics at University of Wisconsin-Madison
bookBachelor of Science (BSc), Bachelor of Science (BSc) at Massachusetts College of Pharmacy and Health Sciences
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Github Skills (12)

nextflow9
pipeline9
python-bindings8
bioinformatics8
data-files8
modular7
genomics7
delimited7
python5
dataframes4
pandas4
numpy3

Programming languages (2)

GroovyPython

Github contributions (5)

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gspracklin/genomics_scripts

Jul 2017 - May 2022

Contributions:28 pushes, 3 branches in 4 years 10 months
gspracklin/hmm_bigwigs

Jan 2019 - May 2020

using hmm on bigwigs
Contributions:16 commits, 7 PRs, 19 pushes in 1 year 4 months
hmm
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George Spracklin - Senior Bioinformatics Engineer