GianniĀ Monaco

Principal Scientist at Sonata Therapeutics

Boston, Massachusetts, United States
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Summary

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Gianni Monaco is a Principal Scientist based in Boston with 11 years of experience applying and developing computational methods to dissect cancer and ageing-related biological data. He combines deep bioinformatics expertise in NGS, microarray, flow cytometry and single-cell/multi-omics analysis with hands-on lab experience in cell isolation and immunophenotyping, enabling tight integration of wet-lab and computational workflows. His work spans algorithm and pipeline development for QC, clustering, deconvolution, network modelling and predictive algorithms for immunotherapy response, including participation in DREAM challenges and neoantigen/TCR repertoire analyses. Having led single-cell and spatial proteomics projects across academic and industry settings, he is adept at turning complex immunological data into actionable biological insight. Notably, he developed flowAI early in his career to automate anomaly detection in flow cytometry data, reflecting a long-standing focus on robust data preprocessing.
code11 years of coding experience
job2 years of employment as a software developer
bookDoctor of Philosophy (PhD), Bioinformatics and System Biology, Doctor of Philosophy (PhD), Bioinformatics and System Biology at University of Liverpool
bookMaster of Science (MSc), Genetics and Biotechnology, Master of Science (MSc), Genetics and Biotechnology at University of Sannio, Benevento
bookBachelor of Science (BSc), Human Biology, Bachelor of Science (BSc), Human Biology at University of Federico II, Naples
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Github Skills (17)

spatial-transcriptomics9
single-cell-analysis8
genes7
gene-expression6
differential-expression5
power-analysis5
seq5
simulate5
transcriptomics4
rna-seq4
bioinformatics3
reduction2
data-exploration1
systems-biology1
clustering1

Programming languages (1)

R

Github contributions (5)

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giannimonaco/ABIS

Aug 2018 - Apr 2020

Contributions:28 commits, 1 PR, 31 pushes in 1 year 8 months
giannimonaco/flowAI

Jun 2018 - Dec 2022

Contributions:49 commits, 4 PRs, 40 pushes in 4 years 6 months
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Gianni Monaco - Principal Scientist at Sonata Therapeutics