Guo-cheng Yuan
Professor at Icahn School of Medicine at Mount Sinai
New York, New York, United States
Summary
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Senior🎓
Top SchoolGuo-cheng Yuan is a computational biologist and professor with over a decade of experience developing computational and network approaches to gene regulation, epigenomics, and single-cell/spatial analysis across development and disease. He leads a lab at Icahn School of Medicine at Mount Sinai that integrates genomic, transcriptomic, and epigenomic data to uncover regulatory mechanisms and cellular heterogeneity, translating basic insights into disease contexts. His career spans faculty roles at Harvard and Dana-Farber, where he pioneered genome-scale nucleosome positioning methods and computational epigenomic tools for stem cell and cancer research. Trained as a PhD in Applied Mathematics, he brings rigorous quantitative modeling and dynamical systems thinking to biological questions, an approach rooted in earlier work on climate and ocean predictability. Colleagues value his collaborative track record across institutions and disciplines, and his group’s focus on spatial single-cell analysis highlights a commitment to resolving regulation in both space and time.
11 years of coding experience
16 years of employment as a software developer
PhD, Applied Mathematics, PhD, Applied Mathematics at University of Maryland
Stackoverflow
1reputation
0reached
0answers
0questions
Github Skills (18)
spatial8
toolbox8
gene-expression5
weighted4
tsne4
lottery4
least-squares3
weighted-graphs3
deconvolution3
datasets2
bioinformatics2
clustering2
cpp2
machine-learning1
python1
Programming languages (4)
Github contributions (5)
gcyuan/diHMM
Jun 2017 - Jul 2022
Contributions:6 commits, 2 PRs, 8 pushes in 5 years 2 months
gcyuan/SCUBA
Dec 2014 - Jul 2022
Contributions:37 commits, 32 pushes, 10 comments in 7 years 8 months
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