GW McElfresh

Computational Biologist

Hillsboro, Oregon, United States
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Summary

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Senior
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Top School
GW McElfresh is a computational biologist with eight years’ experience applying transcriptomics, systems biology, and robust pipeline engineering to infectious disease and immune cell dynamics. Based at OHSU, he combines fault-tolerant preprocessing, frequentist and Bayesian modeling, causal inference, and copula-based integration to extract reproducible insights from heterogeneous omics datasets. He co-developed the rhesus macaque single-cell immune atlas (RIRA) and open-source tools like cellhashR, bridging method development with collaborative resource building. His work spans discovery of protein biomarkers in tuberculosis, Yellow Fever, and HIV/SIV and emphasizes well-structured, team-oriented computation that accelerates translational research. A physicist-and-mathematician by training, he brings quantitative rigor and an eye for scalable, interpretable analyses to complex biological problems.
code8 years of coding experience
bookMissouri State University
bookDoctor of Philosophy - PhD, Computational Biology, Doctor of Philosophy - PhD, Computational Biology at University of Kansas- Center for Computational Biology
bookBachelor's Degree, Physics and Mathematics, Bachelor's Degree, Physics and Mathematics at Drury University
bookUniversity of Missouri
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Github Skills (10)

rna-seq10
seq10
r-package10
bioinformatics9
classification8
genomics6
cran6
single-cell-genomics4
normalization2
spatial2

Programming languages (3)

DockerfileRPython

Github contributions (5)

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Personal Pages
Contributions:12 PRs, 46 pushes, 5 branches in 6 years 10 months
GWMcElfresh/genieinamodel

Oct 2023 - Apr 2025

Contributions:22 PRs, 134 pushes, 23 branches in 1 year 5 months
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GW McElfresh - Computational Biologist