Hongbo Liu

Assistant Professor at University of Rochester

City of Rochester, New York, United States
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Summary

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Senior
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Hongbo Liu is an Assistant Professor at the University of Rochester who leads the HBLiu Lab studying the functional genome in aging and age-related diseases, bringing 13+ years of research experience and over 15 years of technical expertise in bioinformatics, epigenomics, population genetics, and single-cell omics. He has authored 60+ publications including more than 20 papers in top-tier journals such as Nature Genetics, developed over ten widely used bioinformatics tools, and maintains an active reviewer and editorial presence across leading genomics journals. His work spans large-scale epigenomic profiling (WGBS, EPIC arrays, ChIP-seq, ATAC-seq), GWAS and QTL analyses, Mendelian randomization, and single-cell and spatial multi-omics, allowing him to bridge population-level signals with cellular mechanisms of aging. Notably, he transitioned from international academic roles to a US faculty position while sustaining high-impact tool development and cross-disciplinary collaborations, reflecting both translational ambition and computational depth.
code13 years of coding experience
job5 years of employment as a software developer
bookM.S. Biomathematics Bioinformatics and Computational Biology, M.S. Biomathematics Bioinformatics and Computational Biology at Harbin Medical University
bookPh.D Biomathematics Bioinformatics and Computational Biology, Ph.D Biomathematics Bioinformatics and Computational Biology at Harbin Institute of Technology
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Github Skills (19)

seq4
single-cell-analysis4
sequencing4
statistical-genetics3
deconvolution3
ggplot3
bioinformatics3
htmlwidgets2
machine-learning-algorithms2
visualization2
pipeline2
regression2
imputation1
ase1
inference1

Programming languages (2)

RC++

Github contributions (5)

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hbliu/QDCMR

Mar 2013 - Jan 2018

Contributions:12 commits, 5 pushes in 4 years 10 months
hbliu/SMART

Aug 2014 - May 2022

Contributions:7 commits, 3 pushes in 7 years 10 months
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Hongbo Liu - Assistant Professor at University of Rochester