Hossein Asghari
Senior Bioinformatics Engineer
Vancouver, British Columbia, Canada
Summary
👤
Senior🎓
Top SchoolHossein Asghari is a Senior Bioinformatics Engineer with 10 years of experience building high-performance genomics tools and production bioinformatics pipelines. He combines strong algorithmic and C++/Python expertise with practical ML and Linux skills, delivering solutions that prioritize speed and accuracy—evidenced by tools like CircMiner (50x speedup) and heuristic optimizations that tripled performance in core components. His background spans academia and industry, from algorithm design for low-purity tumor CNV detection to productionizing hybrid genome assembly and liquid biopsy analyses. Now at Natera after senior roles at Ocean Genomics, he excels at turning research-grade methods into scalable, maintainable software for real-world genomics. Notably, he repeatedly leverages data structures and algorithmic engineering (Fibonacci heaps, ILP, interval trees) to achieve orders-of-magnitude improvements rarely visible in typical bioinformatics projects.
10 years of coding experience
5 years of employment as a software developer
Bachelor of Science (BS) Computer Software Engineering - School of Computer Engineering, Bachelor of Science (BS) Computer Software Engineering - School of Computer Engineering at University of TehranHigh School Diploma Mathematics and Physics Discipline, High School Diploma Mathematics and Physics Discipline at Allame helli High schoolMaster’s Degree Computer Science - Computational Biology, Master’s Degree Computer Science - Computational Biology at Simon Fraser University
Persian, English
Github Skills (27)
seq10
rna-seq10
bioinformatics10
conda9
genome9
hash9
bioconda8
dbg8
package-management8
gene-expression7
transcript6
transcriptomics5
graph5
converter4
coordinates4
Programming languages (5)
Github contributions (5)
vpc-ccg/circminer
Feb 2018 - Jun 2020
A sensitive and fast tool for circular RNA detection from RNA-Seq data
Contributions:3 releases, 5 reviews, 351 commits in 2 years 4 months
circular-rnabioinformaticscircularsensitiverna-seq
OceanGenomics/pufferfish
Jun 2021 - Sep 2022
An efficient index for the colored, compacted, de Bruijn graph
Contributions:17 pushes in 1 year 3 months
indexcoloredgraphcompacted
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