Hsin-ta Wu

Principal Bioinformatician, Precision Oncology

San Francisco Bay Area United States
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Summary

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Hsin-ta Wu is a PhD-trained computational biologist and bioinformatics leader with 12–15 years of experience translating cancer genomics into diagnostic products, currently serving as Principal Bioinformatician in precision oncology. He has led multi-disciplinary teams at Natera and Aqtual to build ctDNA and cfDNA-based algorithms, NGS pipelines, and machine learning stacks for early cancer detection, recurrence monitoring, and translational studies. His work spans algorithm development, statistical modeling, fragmentomics and epigenomic signal extraction from cfDNA, with multiple high-impact publications and deep experience mining large public datasets like TCGA. Known for pairing hands-on technical contributions with strategic product vision, he has driven platform-level decisions (e.g., Signatera Genome) and led cross-functional scientific partnerships. Based in the San Francisco Bay Area, he brings both academic rigor and product-focused execution to move novel biomarkers from discovery toward clinical utility.
code12 years of coding experience
job8 years of employment as a software developer
bookBS Computer Science, BS Computer Science at National Chengchi University
bookDoctor of Philosophy (PhD) Computer Science and Computational Biology, Doctor of Philosophy (PhD) Computer Science and Computational Biology at Brown University
bookMaster of Science (M.S.) Bioinformatics, Master of Science (M.S.) Bioinformatics at National Yang Ming University
languagesEnglish, Chinese, Japanese
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Stackoverflow

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Github Skills (14)

combinations8
comet7
genomics4
javascript3
d3js2
data-visualization2
visualization2
mutation1
nextjs1
genome1
web-application1
interpretation1
tailwindcss1
react1

Github contributions (5)

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bournewu/GroupNetworkD3

Feb 2016 - May 2017

Contributions:1 PR, 7 pushes, 5 branches in 1 year 2 months
raphael-group/comet

Jan 2015 - Apr 2016

Contributions:22 commits, 5 PRs, 19 pushes in 1 year 3 months
cometexclusiveapproachcombinationsstatistical
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Hsin-ta Wu - Principal Bioinformatician, Precision Oncology