Hsuan-lin Her

Bioinformatics Scientist II

San Diego, California, United States
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Summary

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Senior
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Top School
Hsuan-lin Her is a bioinformatics scientist and ML researcher with 10 years of experience building sequence-to-function models and end-to-end systems that translate regulatory sequence signals into actionable insights. Currently at Guardant Health, Hsuan-lin contributes to FDA regulatory submissions for companion diagnostics while developing LLM-driven retrieval-augmented frameworks to streamline regulatory workflows. With a PhD from UCSD in Bioinformatics & Systems Biology, their work spans large-scale NGS and CLIP-seq analysis, custom loss design for biologically aligned deep learning, and variant effect prediction linked to phenotypes. They combine rigorous model benchmarking and scalable pipelines (Snakemake, CI/CD, PyTorch) with practical productization for variant interpretation and oligonucleotide design. Less obvious: they bridge clinical training as an MD candidate background with advanced computational methods, positioning them to drive translational AI in regulatory genomics and therapeutic development.
code10 years of coding experience
job6 years of employment as a software developer
bookUniversity of California, San Diego
bookDoctor of Medicine - MD, Medicine, Doctor of Medicine - MD, Medicine at Taipei Medical University
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Stackoverflow

Stats
16reputation
57reached
3answers
0questions
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Github Skills (72)

seq10
bootstrap-theme10
clip10
bootstrap10
html9
transcriptomics9
jekyll-theme9
jekyll9
single-cell-analysis8
splice8
open-source8
bioinformatics8
adapter8
duplication7
python7

Programming languages (10)

DockerfileC++ShellRTeXHTMLPerlJupyter Notebook

Github contributions (5)

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algaebrown/resistanceExp

May 2017 - Sep 2021

Contributions:301 commits, 89 pushes, 5 branches in 4 years 4 months
algaebrown/Metadensity

Jun 2020 - Dec 2023

Define metadensity to predict RNA binding protein function
Contributions:1 release, 35 pushes, 1 branch in 3 years 6 months
protein-functionpredictbioinformaticsrna-seqprotein
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Hsuan-lin Her - Bioinformatics Scientist II