Hufeng Zhou
Instructor at Harvard Medical School and Brigham and Women's Hospital
Malden, Massachusetts, United States
Summary
👤
Senior🎓
Top SchoolHufeng Zhou is an interdisciplinary computational biologist and instructor with nine years of research experience bridging statistical genetics, machine learning, and next-generation sequencing to dissect host–pathogen interactions and viral oncology. With a Ph.D. from the National University of Singapore and current roles at Harvard Medical School and Brigham and Women’s Hospital, he leads large-scale WGS and epigenomic analyses—applying ChIP-seq, Hi-C, ChIA-PET, RNA-seq and related assays—to map regulatory architecture in EBV-associated cancers. His work combines rare-variant discovery in massive cohorts (TOPMed, UK Biobank, All of Us) with functional annotation of noncoding variants and cross-species protein–protein interaction modeling to reveal mechanistic links to infection, immunity, and cardiometabolic traits. Hufeng also builds scalable genomics resources (e.g., FAVOR-style tools and databases) and curates pathway and metagenomic data to enable systems-level inference, reflecting a rare blend of computational rigor and translational focus. Notably, his background includes hands-on assay development for viral super-enhancer discovery, underscoring an ability to move from wet-lab designs to population-scale computational insight.
8 years of coding experience
Doctor of Philosophy (Ph.D.), Computational Biology, 4.82/5.00, Doctor of Philosophy (Ph.D.), Computational Biology, 4.82/5.00 at National University of Singapore
Stackoverflow
11reputation
24reached
0answers
1question
Github Skills (15)
bcftools9
samtools9
genomics7
grammar5
typescript4
visualization4
webgl4
svg3
tiled3
scalable2
data-storage1
orientdb1
traits1
abaqus1
r-package1
Programming languages (6)
Github contributions (5)
zhouhufeng/zhouhufeng.github.io
May 2020 - Jun 2023
Contributions:73 pushes, 1 branch in 3 years 2 months
zhouhufeng/FAVORannotator
Nov 2021 - Jul 2022
Contributions:87 commits, 140 pushes, 1 branch in 8 months
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