Ian Outhwaite
MD PhD Candidate
Town of Brookhaven, New York, United States
Summary
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Senior🎓
Top SchoolIan Outhwaite is an MD/PhD candidate and Chemical Biology Fellow at Stony Brook University who applies structural, biochemical, and computational methods to optimize drug-target selectivity for clinically observed kinase mutants. He combines hands-on expertise in single-particle cryo-EM and x-ray crystallography with computational tools he develops, such as Multicompound Multitarget Scoring and SP EM refinement, to link atomic structures to inhibitor design. Previously at Memorial Sloan Kettering he solved high-resolution cryo-EM structures of an activated calcium channel, and as an undergraduate he created an algorithm for identifying core and flexible proteins across genomes. With nine years of research experience, Ian spans protein expression and purification (including transmembrane proteins), enzymology, in-cell NanoBRET validation, and compound docking/SAR workflows. He is comfortable moving between bench and code, routinely integrating structural data into compound refinement pipelines. Based in the Town of Brookhaven, NY, he maintains an active online portfolio showcasing his interdisciplinary projects.
9 years of coding experience
Bachelor of Arts - BA, Biology, Bachelor of Arts - BA, Biology at Williams CollegeMD/PhD, MD/PhD at Stony Brook UniversityProgramming languages (1)
Github contributions (5)
iouthwaite/inhibitor_combinations
Dec 2021 - Mar 2023
Contributions:74 commits, 65 pushes, 2 comments in 1 year 2 months
iouthwaite/iouthwaite.github.io
May 2024 - Jul 2024
Contributions:72 pushes in 2 months
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