Irene Kiburu is a Principal Scientist and structural biologist with 10+ years' experience solving x-ray crystallography and cryo-EM structures of soluble and membrane proteins to illuminate inhibition mechanisms and guide drug design. She combines deep expertise in protein biophysics with hands-on organic synthesis—having developed probes for riboswitches and ligands for OLED materials—bridging chemistry and structural biology in multidisciplinary projects. At Weill Cornell and now Gilead Sciences she led membrane-protein structural efforts, developed novel in-situ LCP crystallography methods and protein-engineering strategies to stabilize challenging targets. Her work has produced de novo structures that clarified sterol transport and mitochondrial protein function, supported NIH grant efforts, and resulted in multiple high-impact publications. Known for mentoring and lab leadership, she also brings a rare blend of teaching excellence and practical synthetic chemistry that accelerates translational research.
10 years of coding experience
9 years of employment as a software developer
Bachelor’s Degree, Chemistry, 3.8/4.0, Bachelor’s Degree, Chemistry, 3.8/4.0 at Rutgers, The State University of New Jersey-Newark
Doctor of Philosophy (Ph.D.), Chemistry and Biochemistry, 4.0/4.0, Doctor of Philosophy (Ph.D.), Chemistry and Biochemistry, 4.0/4.0 at University of Maryland
A Hakyll [plclub] website (https://www.cis.upenn.edu/~plclub/)
Contributions:88 commits, 10 PRs, 43 pushes in 2 years 11 months
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Irene Kiburu - Principal Scientist at Gilead Sciences