Jacob Best

Research Scientist at Van Andel Research Institute

San Francisco, California, United States
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Summary

👤
Senior
🎓
Top School
Jacob Best is a research scientist and software developer with a decade of experience applying computational tools to biological questions, currently based in San Francisco. He transitioned from biochemistry and animal behavior research into software engineering after building custom data-processing tools to extract meaningful results from legacy lab software. His work spans Python data analysis, PostgreSQL-backed data pipelines, and contributions to prominent open-source bioinformatics tooling like MultiQC, where he enhanced BISCUIT parsing and visualization. Jacob combines hands-on lab experience with backend engineering skills to bridge experimental design and reproducible computational reporting. He is motivated by practical problem solving and collaborative teams that translate research needs into robust, user-facing software.
code10 years of coding experience
bookBiochemistry, Mathematics, Biochemistry, Mathematics at Grand Valley State University
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Github Skills (8)

data-visualizations10
bioinformatics10
analyse10
data-visualisation10
data-visualization10
python10
reporting-services10
mu10

Programming languages (9)

RShellC++RustCJavaScriptHTMLCython

Github contributions (5)

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MultiQC/MultiQC

Mar 2020 - May 2021

Aggregate results from bioinformatics analyses across many samples into a single report.
Role in this project:
userBack-end Developer
Contributions:13 commits, 3 PRs, 3 comments in 1 year 2 months
Contributions summary:Jacob updated the `multiqc/modules/biscuit/biscuit.py` module, indicating a focus on integrating or improving the functionality of the BISCUIT tool within the MultiQC framework. These commits involved significant changes to parsing and charting logic, suggesting the user worked on data processing and visualization aspects related to bioinformatics analyses. The changes included modifications to the structure and presentation of the output, including several new charts and table visualizations. The commits indicate the user's role in developing and maintaining components that handle and report on data derived from the BISCUIT tool.
multiqcpythonpypianalysesbioconda
Snakemake Workflow For Running Biscuit https://github.com/huishenlab/biscuit
Contributions:5 releases, 2 reviews, 3 PRs in 2 years 6 months
snakemake-workflowwgbsbiscuitsnakemakemethylation
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Jacob Best - Research Scientist at Van Andel Research Institute