Jacob Leander
Director, Clinical Pharmacology And Pharmacometrics at AstraZeneca
Gothenburg, Sweden
Summary
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Senior🎓
Top SchoolJacob Leander is a Director of Clinical Pharmacology and Pharmacometrics at AstraZeneca with 12 years' experience applying advanced mathematical modeling to accelerate drug development from Phase 1 through Phase 3 and regulatory defense. He holds a PhD in Applied Mathematics and Mathematical Statistics and has authored 11 peer-reviewed articles plus the exact gradient FOCE algorithm implemented in NONMEM 7.4. Jacob combines deep technical expertise in R, NONMEM, Monolix, MATLAB and C++ with hands-on experience across small molecules and biologics, and he led platform transitions and mentoring efforts within clinical pharmacology teams. His background in hierarchical and stochastic dynamical systems informs pragmatic model-informed drug development and optimal study design. Based in Gothenburg, he brings a rare blend of academic rigor and practical regulatory-facing delivery.
12 years of coding experience
11 years of employment as a software developer
PhD Applied Mathematics and Mathematical Statistics, PhD Applied Mathematics and Mathematical Statistics at Chalmers University of Technology
Swedish, English, French
Github Skills (4)
r-package2
python1
modeling1
project-management1
Programming languages (2)
Github contributions (5)
karnstrand/Kalman4J
Dec 2013 - Feb 2015
Contributions:14 commits, 12 pushes in 1 year 2 months
jacobleander/jacobleander.github.io
Nov 2020 - May 2023
Github Pages template for academic personal websites, forked from mmistakes/minimal-mistakes
Contributions:38 pushes in 2 years 6 months
templategithub-pages-templatemmistakesmistakesjekyll
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