Jacob Luber

Associate Member (Associate Professor)

Boston, Massachusetts, United States
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Summary

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Senior
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Top School
Jacob Luber is an associate professor and computational biologist who builds scalable tools to contextualize cancer imaging and high-throughput omics data for both clinical decision support and drug discovery. With 11 years of experience bridging computer science and bioengineering, he develops statistical and machine learning frameworks for single-cell and spatial transcriptomics, spatial proteomics (CODEX), and calcium imaging at massive scale. His lab’s focus on translating imaging and multi-omics into actionable oncology insights complements his recent academic transition to St. Jude Children’s Research Hospital, highlighting a growing emphasis on pediatric cancer applications. Trained in Bioinformatics and Integrative Genomics at Harvard Medical School and grounded in computer science from Trinity University, he pairs rigorous computational methods with domain-driven experimental collaboration. Notably, his early work on PDX models and drug-response biomarkers demonstrates a practical track record of moving algorithms toward translational impact.
code11 years of coding experience
job7 years of employment as a software developer
bookDoctor of Philosophy (Ph.D.) Bioinformatics and Integrative Genomics (BIG) Program, Doctor of Philosophy (Ph.D.) Bioinformatics and Integrative Genomics (BIG) Program at Harvard Medical School
bookBachelor of Science - BS Computer Science, Bachelor of Science - BS Computer Science at Trinity University
bookThe Lawrenceville School
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Github Skills (11)

genomics8
tiled7
bioinformatics6
numerical-optimization6
python6
science6
pipeline5
cloud-computing5
rna-seq4
rna-velocity1
deep-learning1

Programming languages (2)

Jupyter NotebookPython

Github contributions (5)

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kosticlab/aether

Jul 2017 - Dec 2017

Intelligent and cost-effective bidding on cloud computing instances for bioinformatics pipelines.
Contributions:2 releases, 37 commits, 2 PRs in 5 months
bioinformaticscloud-computingdistributedpythonscience
jacobluber/luberlab

Sep 2021 - Apr 2025

Allan Lab website
Contributions:121 pushes in 3 years 7 months
lablab-website
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