Jake Gockley

Senior Principle Scientist at Regeneron

Seattle, Washington, United States
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Summary

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Senior
🎓
Top School
Jake Gockley is a Senior Principal Scientist with a decade of experience melding bench science and computational genetics to build end-to-end high-throughput sequencing and functional genomics pipelines. He led development of a scalable enhancer screen that assayed over 100,000 candidate sequences and has driven integrative analyses across 10x Chromium WGS, RNA-Seq, and CyTOF data in cancer cohorts. His expertise spans SNVs, INDELs, CNVs and complex structural variant analysis, and he repeatedly translates large-scale genomics readouts into actionable biomarker insights for translational and clinical studies. Comfortable in Python and R and increasingly focused on TensorFlow/Keras, he is expanding into deconvolutional and recurrent neural network applications for multi-modal biological data. Based in Seattle, Jake pairs deep experimental know-how from his Yale Ph.D. with production-focused computational rigor developed at Regeneron, Sage Bionetworks, and Celgene. An uncommon strength is his track record of processing billions of reads into reproducible discovery pipelines that bridge evolutionary biology and human disease.
code10 years of coding experience
job13 years of employment as a software developer
bookBachelor of Science (BS) Biology General, Bachelor of Science (BS) Biology General at University of Vermont
bookYale University
languagesSpanish, Portuguese
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Github Skills (47)

rna-seq10
vcenter10
csharp7
loss6
seq6
seccomp6
netbox5
imputation5
commons5
sandbox5
junction4
convolutional-neural-networks4
toolbox4
bioinformatics4
causal4

Programming languages (8)

DockerfileRShellCSSJinjaC++Jupyter NotebookPython

Github contributions (5)

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Sage-Bionetworks/sageseqr

Apr 2020 - Apr 2022

A workflow for exploring and analyzing RNA-seq data.
Contributions:28 reviews, 159 commits, 29 PRs in 1 year 11 months
rna-seq
A sandbox repository for Pathway Commons
Contributions:120 commits, 23 PRs, 125 pushes in 2 years
commonspathwaytoolboxnetboxsandbox
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