Jake Gockley

Senior Principle Scientist at Regeneron

Seattle, Washington, United States
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Summary

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Senior
🎓
Top School
Jake Gockley is a Senior Principal Scientist with a decade of experience melding bench science and computational genetics to build end-to-end high-throughput sequencing and functional genomics pipelines. He led development of a scalable enhancer screen that assayed over 100,000 candidate sequences and has driven integrative analyses across 10x Chromium WGS, RNA-Seq, and CyTOF data in cancer cohorts. His expertise spans SNVs, INDELs, CNVs and complex structural variant analysis, and he repeatedly translates large-scale genomics readouts into actionable biomarker insights for translational and clinical studies. Comfortable in Python and R and increasingly focused on TensorFlow/Keras, he is expanding into deconvolutional and recurrent neural network applications for multi-modal biological data. Based in Seattle, Jake pairs deep experimental know-how from his Yale Ph.D. with production-focused computational rigor developed at Regeneron, Sage Bionetworks, and Celgene. An uncommon strength is his track record of processing billions of reads into reproducible discovery pipelines that bridge evolutionary biology and human disease.
code10 years of coding experience
job13 years of employment as a software developer
bookBachelor of Science (BS) Biology General, Bachelor of Science (BS) Biology General at University of Vermont
bookYale University
languagesSpanish, Portuguese
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Github Skills (54)

seq10
rna-seq10
vcenter10
bioinformatics9
pipeline7
loss6
sequential6
csharp6
sandbox6
seccomp6
netbox5
sage4
commons4
cancer-genomics4
toolbox4

Programming languages (8)

DockerfileC++RJinjaCSSShellJupyter NotebookPython

Github contributions (5)

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Sage-Bionetworks/sageseqr

Apr 2020 - Apr 2022

A workflow for exploring and analyzing RNA-seq data.
Contributions:28 reviews, 159 commits, 29 PRs in 1 year 11 months
analyzingpipelinebioinformaticsrna-seqrna-seq-data
jgockley62/TWAS

Sep 2019 - Oct 2023

Processing of TWAS Data
Contributions:4 PRs, 130 pushes, 2 branches in 4 years 1 month
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Jake Gockley - Senior Principle Scientist at Regeneron