James Macdonald

Biostatistician

Ann Arbor, Michigan, United States
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Summary

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Senior
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Top School
James Macdonald is a biostatistician with 20 years of experience specializing in high-throughput and OMICs data analysis, including RNA-Seq, DNA-Seq, ChIP-Seq, methylation, proteomics, and metabolomics. Based in Ann Arbor, he has spent over a decade as a core contributor to Bioconductor, developing and deploying R-based tools that enable reproducible, cutting-edge analyses for the genomics community. He combines deep statistical training (Master’s in Biostatistics, Univ. of Michigan) with hands-on computational skills in R, Perl, and Linux command-line workflows required for modern sequencing pipelines. His background in microbiology gives him practical domain insight when translating experimental design into robust analytical strategies. At academic centers including the University of Michigan and University of Washington, he has supported diverse projects from immunoassays to mass-spec, consistently bridging method development and applied analysis. Colleagues rely on him for reproducible, production-ready pipelines that handle complex, heterogeneous biological datasets.
code21 years of coding experience
bookMaster's degree, Biostatistics, Master's degree, Biostatistics at University of Michigan
bookBachelor of Science (BS), Microbiology, Bachelor of Science (BS), Microbiology at Colorado State University
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Github Skills (36)

bioconductor10
biomart10
core-package10
r-package9
genomics9
rna-seq8
genome-annotation8
webservice8
uniprot8
bioinformatics8
r8
plot7
gene-expression7
sqlite7
core-services5

Programming languages (10)

DockerfileRC++CSSCRustTeXJavaScript

Github contributions (5)

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jmacdon/methylation

Oct 2013 - Oct 2015

Contributions:34 commits, 1 PR, 12 pushes in 2 years
methylationilluminaarrays
jmacdon/affycoretools

Aug 2017 - Sep 2025

Contributions:53 pushes, 8 branches, 1 comment in 8 years 2 months
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