Jan Blecha
Process Development Specialist In SCT Cell Manufacturing at SCT Cell Manufacturing s.r.o.
Prague, Prague, Czechia
Summary
🤩
Rockstar🎓
Top SchoolJan Blecha is a Process Development Specialist in cell manufacturing with 13 years of hands-on experience bridging molecular biology research and GMP-compliant production of cell- and gene-based therapies. With a PhD in molecular biology from Charles University and a strong background in flow cytometry, confocal microscopy, cellular respirometry and metabolic assays, he designs and optimizes manufacturing processes, control strategies and analytical methods for immuno-hematopoietic products. He brings practical GMP lab leadership—troubleshooting instruments, advising on process transfer, and coordinating vendors—with a scientist’s rigor from prior academic work on anticancer drug mechanisms and mitochondrial biology. Jan also contributes to open-source scientific computing projects (notably meshio and dolfinx), showing uncommon cross-discipline fluency between biotech workflows and backend software development. Colleagues describe him as an independent, creative problem solver who prefers collaborative teams and turns complex experimental challenges into robust, auditable processes.
13 years of coding experience
fourth year of PhD. study, Molecular Biology, 4. year of PhD. study, fourth year of PhD. study, Molecular Biology, 4. year of PhD. study at Charles University in Prague
English, German, Czech
Github Skills (15)
file-handling10
file-processing10
finite-element-analysis10
mesh10
c-language10
parallel-computing10
file-access10
cprogramming-language10
python10
fileio10
mesh-processing10
math9
partial-differential-equations9
mathematics9
mpi9
Programming languages (7)
Github contributions (5)
FEniCS/dolfinx
Feb 2018 - Aug 2018
Next generation FEniCS problem solving environment for solving finite element problems
Role in this project:
Back-end Developer
Back-end DeveloperContributions:14 commits, 16 PRs, 19 pushes in 5 months
Contributions summary:Jan primarily contributed to the core functionality of the dolfinx project. Their commits involve modifications to the internal workings of the FEniCS problem-solving environment, including fixing issues with the pkgconfig, updates to the UFC, and adjusting dependencies. Furthermore, the user worked on the build process and versioning. The user has also contributed to the demo documentation and the underlying library by making changes to support different elements and dependencies.
fenicsfinite-element-methodspartial-differential-equationsparallel-computingfenicsx
nschloe/meshio
Sep 2018 - Sep 2018
:spider_web: input/output for many mesh formats
Role in this project:Back-end Developer
Back-end DeveloperContributions:7 commits, 1 PR, 2 comments in 1 day
Contributions summary:Jan contributed to the `meshio` library by implementing support for additional mesh file formats, specifically focusing on Xdmf variations (binary, HDF, XML). They also refactored the code to pass keyword arguments through write functions, providing more flexibility. Furthermore, they fixed a bug in the `write()` function and improved code quality by removing debug statements and standardizing quote usage with a tool.
meshinput-outputpythonpypispider
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